Clinical Nurse III - MultiSpecialty Clinic

City of Hope
City of Hope

Irvine, CA, USA

Posted on Nov 14, 2026

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.

In this clinic-based role, you will work alongside the provider in a high-acuity, fast-paced ambulatory setting, caring for complex patients requiring advanced therapies. As a key member of the care team, the RN will play an integral role in care coordination—providing patient education on treatment plans, closely monitoring laboratory results, and coordinating transfusions as needed. You will collaborate closely with the physician and the Advanced Practice Provider to triage patient needs, follow up on orders, and manage in-basket communications to ensure timely, comprehensive, and high-quality care.

The ideal candidate will demonstrate strong clinical expertise, attention to detail, and a compassionate, patient-centered approach while working in a fast-paced, multidisciplinary environment. This position is Monday – Friday 8am – 630pm

As a successful candidate, you will:

  • Coordinate and provide age-appropriate, patient centered care in an oncology and multi-specialty clinic: (endocrinology, pain management, integrative medicine, gastroenterology, cardiology, acupuncture, and survivorship)
  • Collaborate with oncology specialists and other multidisciplinary teams to develop and adjust treatment plans based on the patient’s progress and needs.
  • Perform pre-procedure phone calls for appointments
  • Triage patient concerns via telephone and inbox messages using established protocols by documenting all encounters with EMR
  • Promote wellness and prevention strategies to oncology patients, ensuring they are equipped with knowledge about self-care and survivorship.
  • Facilitate prescription refills according to refill protocols, utilizing electronic prescriptions.
  • Assist patients navigate survivorship care, by providing education and resources to patients and families.
  • Uses evidence-based practice and best available research to inform practice.
  • Enhances professional growth and development.
  • Participates in unit-based projects and activities, staff meetings, councils, work teams.
  • Reviews current literature attends educational programs, workshops, and in-services.
  • Actively participates in shared decision-making / participative leadership through councils, committees, work teams, task forces, and unit-based practice councils.

Qualifications

Your qualifications should include:

  • Bachelor’s degree or master’s degree in nursing is required.

  • Three to five years related experience

  • Current Registered Nurse license

  • Current Basic Life Support (BLS) through the American Heart Association

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

Please note: City of Hope is committed to a safe and transparent hiring experience. Please be aware that scammers may attempt to impersonate our organization through fake job postings, emails or interviews.

  • Apply only through our official website or trusted partner platforms.
  • City of Hope will never request payment or fees at any stage of the hiring process.
  • We will not request sensitive personal or financial information prior to the acceptance of a formal offer.
  • All communications will come from official @coh.org email addresses.
  • Interviews are conducted only through approved, professional channels.
  • Be cautious of unsolicited communications, urgent requests or opportunities that seem inconsistent with standard hiring practices.
  • If you receive any suspicious communication, please report it to [email protected].